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On-X Life Technologies, Inc. is a wholly owned subsidiary of CryoLife, Inc. The On-X Prosthetic Heart Valves are manufactured by On-X Life Technologies, Inc. The snowflake design, CryoLife, Life Restoring Technologies, and On-X are registered trademarks owned by CryoLife, Inc. or its subsidiaries. All other registered trademarks are owned by their respective owners. © 2021 CryoLife, Inc. All rights reserved. MLENG1484.000 (2021-08)

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Guidelines for Valve Replacement

The American Heart Association and American College of Cardiology guidelines for valve replacement say that mechanical valves are reasonable for patients 70 and younger, while tissue valves are reasonable for patients 50 and older.1

Tissue valves typically last up to 15 years, and often less in younger patients. Some tissue valves fail after 4 to 6 years in patients less than 65 years old. Some tissue valves fail after 7 to 10 years in patients greater than 65 years. 2 Over time, tissue valves will likely degenerate to the point of requiring replacement. The primary advantage of mechanical valves is that they will typically last a patient’s lifetime. Because of this, mechanical valves are often selected for patients with life expectancies beyond 10-15 years.

  1. Nishimura R et al., 2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients with Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2017;135:e1159-95.
  2. Wang M et al., Ann Thorac Surg 2017; pii: S0003-4975(17)30266-7.